Sok od grejpfruta može povećati koncentraciju diazepama u Vašoj krvi. Ukoliko ste starijeg životnog doba, imate cirozu jetre ili bilo koje stanje navedeno u odeljku 2, dejstvo leka Bensedin može biti pojačano, pa je potrebno da o tome obavestite Vašeg lekara ili farmaceuta.
Using this medicine with any of the next medicines is not really recommended. Your health care provider may possibly make your mind up not to deal with you using this type of medication or modify a few of the other medicines you're taking.
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I was prescribed bensedin by my medical doctor immediately after owning experienced a lot. The medicine turned out to become really valuable, and I am incredibly grateful towards the medical professional. It actually served me get my existence again heading in the right direction. Thanks.
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Istovremena primena leka Bensedin i opioida (lekova za ublažavanje jakih bolova, lekova za supstitucionu terapiji i određenih lekova protiv kašlja) povećava rizik od pospanosti, otežanog disanja (respiratorna depresija), kome što sve može biti životno ugrožavajuće. Zbog toga istovremenu primenu treba razmotriti samo ukoliko druge terapijske opcije nisu moguće.
Bensedin tablets are also called Diazepam that belongs to the class of medicines identified as benzodiazepines.
Dejstvo benzodiazepina može biti pojačano i produženo prilikom istovremene upotrebe. Može biti potrebno smanjenje doze benzodiazepina.
Zavisnost - prilikom uzimanja ovog leka postoji rizik od razvoja zavisnosti, koji raste sa povećanjem doze i dužine trajanja terapije. Rizik je veći kod pacijenata koji su ranije read more bili zavisni od alkohola ili lekova. Zbog toga lek Bensedin treba uzimati što je moguće kraći vremenski period of time.
Karbamazepin je poznati induktor CYP3A4 i ubrzava metabolizam diazepama u jetri. Ovo može rezultirati trostrukim povećanjem klirensa iz plazme i skraćenjem poluvremena eliminacije diazepama. Smanjeno dejstvo diazepama.
U malom broju slučajeva, prijavljeno je da je istovremena primena sa diazepamom smanjila dejstvo levodope.
Istovremena primena lekova sa sedativnim efektom poput benzodiazepina ili sličnih lekova kao što je diazepam sa opioidima povećava rizik od sedacije, respiratorne depresije, kome i smrti, usled aditivnih depresivnih efekata na CNS. Treba ograničiti doziranje i trajanje istovremene terapije (videti odeljak four.4).
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